Patil Hospital, Dr. Background: The study was designed to explore lipid profile and electrocardiographic changes associated with thyroid dysfunctions. Materials and Methods: A total of 72 patients of thyroid dysfunction having either hypothyroidism or hyperthyroidism were investigated with lipid profiles and electrocardiogram ECG.
Levothyroxine therapy is the traditional lifelong replacement therapy for hypothyroid patients. Over the last several years, new evidence has led clinicians to evaluate the option of combined T 3 and T 4 treatment to improve the quality of life, cognition, and peripheral parameters of thyroid hormone action in hypothyroidism. The aim of this review is to assess the physiological basis and the results of current studies on this topic.
Disease of the thyroid gland often produces heart problems. One of the most important reasons to diagnose and treat thyroid disease is to prevent the cardiac conditions that can result from it. By producing just the right amount of thyroid hormone, the thyroid helps to regulate your body's metabolism—most importantly, how much oxygen and energy your body uses—as well as your digestive function, muscle function, and skin tone.
The journal, published sinceis the official publication of the Spanish Society of Cardiology and founder of the REC Publications journal family. Articles are published in both English an Spanish in its electronic edition. The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two receding years. CiteScore measures average citations received per document published.
The cardiovascular system is one of the most important targets of thyroid hormones 12 and is very sensitive to a minimal decrease of circulating thyroid hormones 2. It has long been recognized that hypothyroidism may cause cardiac pathologies, such as impaired cardiac contractility, decreased cardiac output, increased systemic vascular resistance, and cardiac electrical abnormalities 34. Electrocardiographic changes such as bradycardia, low voltage, and varying degrees of heart block are commonly recognized in hypothyroid patients 1.
One of the most important thyroid hormone targets is the cardiovascular system. Hemodynamic changes, such as decreased resting heart rate HRmyocardial contractility, and cardiac output, and increased diastolic pressure and systemic vascular resistance, have been observed in hypothyroid patients. This study aimed at evaluating the prophylactic effect of apelin on HR changes and QRS voltage that occur in propylthiouracil PTU -induced hypothyroid rats.
Thyroid parameters median thyrotropin, mean free thyroxine [FT 4 ], and mean total triiodothyronine [T 3 ] during treatment. Error bars indicate SD. To convert FT 4 to picomoles per liter, multiply by
Establishing the diagnosis of hypothyroidism is, with a few very important caveats, straightforward. The decision to test for hypothyroidism should be based on various aspects of the clinical picture. Hypothyroidism can present in a myriad of ways.
The heart is very sensitive to even small changes in the levels of thyroid hormones. The heart is a muscle and contains receptors for thyroid hormone, hence heart muscle growth and cardiac function may be influenced by too much or too little thyroid hormone. There is increasing evidence that even small changes in levels of thyroid hormone may be associated with measurable changes in how well the heart functions.